Program
Two
60-minute Plenary
Lectures
Three
Poster Sessions
Eleven
Oral Sessions with
Twenty
Speaker presentations (40-minute talks) and
Eighteen
Short Talks (15-minute presentations selected
from the abstracts submitted for poster presentations by the Scientific
Committee).
Sunday, October 24th
3:00
PM Registration opens at the main Lobby.
7:45
PM - 8:00 PM: Welcome speech
J.
Silvio Gutkind, National Institutes of Health, Bethesda MD, USA.
G Protein-Regulated Signaling Networks in Cancer Progression and Metastasis:
A Synthetic Biology Approach
9:00
PM: Welcome Reception.
Monday,
October 25th
8:40
AM – 10:50 AM Session # 1: all sessions will be held at the SUM Room
(a
5 minute interval is allocated between talks to allow for questions from the
audience.)
8:40
AM – 9:20 AM: Lucio Castilla Univ. of Massachusetts Med. School, USA.
Oncogenic
role of microRNA
17-92 cluster in acute myeloid leukemia
9:25
AM – 10:05 AM: Celine Gales INSERM, Toulouse, France.
New paradigm
in ligand-directed trafficking of GPCRs: AT1
receptor example
10:10 AM – 10:25 AM: Juan Jose
Bonfiglio. FCEN – University of Buenos Aires.
CRH SIGNALING IN THE CENTRAL NERVOUS
SYSTEM: UNDERSTANDING MAPKs ACTIVATION
Activation of Fyn Kinase by Apotransferrin is
Essential for Oligodendrocyte Differentiation
Oxidative
signaling, microRNA
and stem cells
12:05 AM – 12:20 PM: Elba Vazquez FCEN – University of Buenos Aires. Argentina.
HO-1 as a new
player in prostate cancer progression
12:25
AM – 1:05 PM: Sarah Spiegel Virginia Commonwealth University, USA.
Novel
Intracellular Targets of Sphingosine-1-Phosphate
1:10 PM – 1:25 PM: Laila Suhaiman. Fac. Ccias. Med.
UNCuyo-CCT, Mendoza. Argentina
Exocytosis is triggered by
sphingosine 1-phosphate through the activation of S1PR type 1 and 3
1:30
PM – 3:00 PM Lunch at the “Anexo Hotel FATAGA”.
3:00
PM – 4:50 PM Session # 3:
3:00
PM – 3:40 PM Nancy Hynes. F.M. Inst. for Biomed. Research, Switzerland.
Targeting
receptor tyrosine kinases in breast cancer
Oncogenic tyrosine
kinase networks: Defective feedback regulation of signal transduction
4:30
PM – 4:45 PM Jimena Giudice. FCEN – University
of Buenos Aires. Argentina.
Spatio-temporal
dynamics of endocytosis and signaling of insulin receptor A and B
4:50
PM – 5:20 PM Coffee Break
5:20
PM – 7:30 PM: Session # 4:
5:20 PM – 6:00 PM Angel Nebreda IRB-Barcelona, Spain.
Signal
Integration by p38 MAPKs
6:05
PM – 6:20 PM Maria Sol Degese. FCEN – University
of Buenos Aires. Argentina.
The p38 MAPK pathway promotes cFOS mRNA decay
MAPKAP
kinases MK2 and MK3 in inflammation and beyond
The RNA
destabilizing factor and tumor suppressor gene TTP is induced by prolactin in
mammary cells
Tuesday,
October 26th
7:00
AM - 8:30 AM Breakfast at the “Anexo Hotel FATAGA”.
8:40
AM – 10:50 AM Session # 5:
8:40
AM – 9:20 AM: Bernd Groner Georg Speyer Haus Institute, Frankfurt, Germany.
Stat3
and Stat5: oncogenic transcription factors and targets for tumor therapy
9:25
AM – 10:05 AM: Melanie Cobb Univ. of Texas, Southwestern
Med. Center, Dallas, USA.
Coming
full cERKle
on lung cancer
10:10
AM – 10:25 AM: Adriana De Siervi. FCEN – University
of Buenos Aires. Argentina
Cyclin T1: a
new oncogenic protein
10:30
AM – 10:45 AM: Guadalupe Lorenzatti, FCQ –
Universidad de Córdoba. Argentina
SELECTIVE SIGNALING PATHWAYS PARTICIPATE IN THE
REGULATION OF THE BIOLOGICAL ROLE OF ZEB1
11:20
AM - 1:30 PM Session # 6:
The
Glucocorticoid Receptor: A South American Perspective
12:05
PM – 12:45 PM: Ana Aranda Iriarte Inst. de Inv. Med., Madrid, Spain.
The
thyroid hormone receptors as regulators of cell proliferation and malignant
transformation
12:50 PM – 1:05 PM: Luciana Rocha Viegas. FCEN – University of Buenos Aires. Argentina
Role of UTX in
RAR-mediated gene regulation in leukemia
1:10 PM – 1:25 PM: Virginia Novaro . Inst. IBYME – Buenos
Aires. Argentina.
PI3K/AKT
pathway regulates hormone sensitivity and differentiation in a mouse mammary
tumor modeL
1:30
PM – 3:00 PM Lunch at the “Anexo Hotel FATAGA”.
Wednesday,
October 27th
7:00
AM - 8:30 AM Breakfast at the “Anexo Hotel FATAGA”.
8:40
AM – 9:20 AM: Channing Der Univ. of North Carolina, Chapel
Hill, USA.
Targeting the Ral
guanine nucleotide exchange factor (RalGEF)-Ral small GTPase effector pathway
for the development of anti-Ras inhibitors for cancer treatment
9:25
AM – 10:05 AM: Piero Crespo Univ. de Cantabria, Santander, Spain.
Spatial
regulation of ERK1/2 MAP kinases: novel nuclear and cytoplamic events
Strategies to develop novel
anti-Rho GTPase compounds with antitumoral activity
10:30 AM – 10:45 AM: Verónica
Andreoli. FCQ – Universidad de Cordoba. Argentina
KLF6 tumor suppressor engages c-Jun
oncoprotein in an apoptotic pathway through JNK2 phosphorylation
11:20
AM – 12:00 PM: Pablo Visconti Univ. of Massachusetts, Amherst, USA.
Phosphorylation
Events During Sperm Capacitation
Tyrosine phosphatase SHP2 regulates
arachidonic acid (AA) metabolism and mitochondria rearrangement
12:25 PM – 1:05 PM: Heidi Tissenbaum Univ. of Massachusetts Med. School,
USA
Using C. elegans to identify new
modulators of insulin/IGF-1 signaling
1:10 PM – 1:25 PM: Graciela Boccaccio, Fundacion Insituto Leloir. Argentina.
A kinase and phosphatase-wide RNAi screen identifies
regulators of Stress Granule dynamics
1:30
PM – 3:00 PM Lunch at the “Anexo Hotel FATAGA”.
3:00
PM – 5:10 PM Session # 9
3:00
PM – 3:40 PM: Marcelo Kazanietz Univ. of Pennsylvania, USA.
Diacylglycerol
and Rac signaling in cancer progression
3:45
PM – 4:25 PM: Xose Bustelo CIC, Salamanca, Spain.
The
Vav oncoprotein family as anti-cancer targets: positive and negative lights
4:30 PM – 4:45 PM Fiorella Galello FCEN – University of Buenos Aires. Argentina
Identification of proteins that
interact with PKA Regulatory subunit from Saccharomyces
cerevisiae
Nitric oxide synthases trafficking
into mitochondria in the control of cell metabolism and fate
5:10 PM – 5:30 PM
Coffee Break
5:30
PM – 6:30 PM: Plenary Lecture:
Roger
Davis, University of
Metabolic stress
regulation of the JNK signal transduction pathway
6:45
PM 8:30 PM– Poster Session.
9:00
PM – onwards (Traditional Barbecue – ASADO)
Thursday,
October 28th
7:00
AM - 9:00 AM Breakfast at the “Anexo Hotel FATAGA”.
9:00
AM – 12:00 PM Session # 10
9:00
AM – 9:40 AM: Enrique A. Mesri Univ. of
A
Rac1 mediated oxidative stress loop in paracrine viral oncogenesis of Kaposi's
sarcoma identifies novel therapeutic targets
9:45 AM – 10:15 AM: Lic Guido Bonino, RAICES y Dr. Enrique A. Mesri,
CAPICCyTE-RAICES y Consulado Argentino en Miami.
ACTIVIDADES
DEL PROGRAMA RAICES EN VINCULACION Y COOPERACION CIENTIFICA INTERNACIONAL. THE RAICES PROGRAM FOR INTERNATIONAL SCIENTIFIC
COOPERATION WITH ARGENTINA
10:20 AM – 10:50 AM
Coffee Break
10:50 AM – 11:30 AM: Ana Cuenda Centro Nacional de Biotecnología/CSIC, Spain.
Alternative
p38g and p38d pathways in the
immune response
11: 35 AM – 11:50 AM: Ruth Angélica
Lezama Palacios, Escuela Nac. de Cs. Biologicas IPN-México.
Evaluation of
anti-apoptotic pathway in Bcr-abl +/- acute lymphoblastic cells
11:50
AM – 12:00 PM: Closing Remarks:
Omar
Coso, University of Buenos Aires, Buenos
Aires, Argentina.
Farewell lunch and Meeting Adjourns –
busses will transport participants to the airport.